- The increase in the release of calcium from bone, calcium reabsorption from the kidneys and intestinal absorption of calcium.
- reduce the incidence of metabolic disorders, especially milk fever followed by other metabolic disorders
- Reduce uterine diseases such as metritis and retained placenta.
- Reduce mortality and culling in dairy herds
- Increasing milk yield
- Improving economic index herd
Dry period regarded as a critical stage in the life cycle of dairy cows. In this period of increased metabolic stress such as; fetal weight gain, severe hormonal changes and decreasing dry matter intake postpartum increase risk of metabolic disorders (such as milk fever, Displaced Abomasum, ketosis, fatty liver, etc.). However, imbalance of nutrients and dietary cation-anion difference (DCAD) can exacerbated incidence of metabolic disorders especially milk fever and consequently other metabolic disorders. Hypocalcaemia or milk fever is a metabolic disorder associated with a sharp drop of blood serum calcium. It is essential that using anionic salts to prevent from metabolic diseases before calving. The anionic salts used in this premix are highest quality resource. It has been formulated, as, have a least effect on dry matter intake. In addition, DCAD is preserved in range between -100 to -150 Meq/kg DM by using premix. Subsequently, decrease incidence of metabolic disorders significantly. Anionic compounds also will prevented indirectly retained placenta and uterine infections.
Anionic salts declined milk fever incidence risk through change of calcium metabolism. Acidosis increase the sensitivity of tissues (including bones) to parathyroid hormone (PTH) that leads to break down of hydroxyapatite bones and finally, it occur uptake of calcium from bones. In addition, anionic salts affects the kidneys to increase the production of 1, 25- dihydroxy cholecalciferol. The active form of vitamin D in two ways to maintain or raise the level of blood calcium: 1) Affects collecting duct of nephrons and due to increasing uptake of calcium from the urine. 2) Stimulating the production of calcium binding protein and increasing calcium absorption in the intestinal epithelial cells.